Hubungan Leukosit Preoperatif Dengan Lama Penyembuhan Luka Kulit Pada Fraktur Terbuka Ekstremitas Bawah : Implikasi Terhadap Debridement
DOI:
https://doi.org/10.59680/anestesi.v4i2.2474Keywords:
Open fractures, leukocyte, wound healing, lower extremity, inflammationAbstract
Open lower extremity fractures are often associated with extensive soft tissue injury, contamination, and systemic inflammatory responses that may affect postoperative wound healing. Debridement plays a key role in removing devitalized tissue and reducing inflammatory burden. Preoperative leukocyte levels reflect the degree of inflammation and may indicate wound condition. This study aimed to determine the relationship between preoperative leukocyte levels and postoperative wound healing duration and to evaluate their clinical implication in the context of debridement. This observational analytic study used a cross-sectional design involving 84 patients with open lower extremity fractures selected using purposive sampling. Data were obtained from medical records and analyzed using Spearman correlation. The results showed a moderate positive correlation between preoperative leukocyte levels and wound healing duration (r = 0.514; p < 0.05). Higher leukocyte levels were associated with longer wound healing time. In conclusion, preoperative leukocyte levels are significantly associated with wound healing duration and may serve as an early clinical indicator to optimize debridement strategies in open fracture management.
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Copyright (c) 2026 Shabrina Amalia Salsabila, Prima Maharani Putri, Paramita Septianawati, Yusuf Adi Gunawan
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