The Relationship Between Prostate Specific Antigen (PSA) Levels and Gleason Score in Prostate Cancer Patients at Dr. Pirngadi Regional Hospital Medan City
DOI:
https://doi.org/10.59680/anestesi.v4i2.2404Keywords:
Prostate Cancer, Prostate-Specific Antigen (PSA), Gleason Score, Korelasi Spearman, Diferensiasi TumorAbstract
PSA is a glycoprotein produced by epithelial cells in the prostate gland and ducts. In prostate cancer patients, PSA levels are generally elevated. The most commonly used tumor cell differentiation assessment system is the Gleason Score. This study used a retrospective analytical observational study design with a cross-sectional design approach using medical record data. Based on the results of the study conducted at Dr. Pirngadi Regional Hospital, Medan City, 71 samples were obtained. The highest incidence of prostate cancer was in the age range of 61-70 years, as many as 28 people (39.44%). The most common prostate specific antigen (PSA) level was >20 mg/ml (53.5%), and the most common Gleason score was poorly differentiated (57.7%). Spearman correlation results showed a significant relationship between prostate-specific antigen (PSA) levels and Gleason score in prostate cancer patients (p=0.003), with a correlation coefficient (r=0.347) indicating a sufficient correlation, where a positive correlation coefficient value indicates a directional relationship between the two variables. There is a significant relationship between prostate-specific antigen (PSA) levels and Gleason score in prostate cancer patients.
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