Gambaran Klinikopatologi Karsinoma Laring di Laboatorium Patologi Anatomi RSUP. Dr. M. Djamil Padang Tahun 2018 -2021

Authors

  • Fikri Akbar Universitas Andalas
  • Ade Asyari Universitas Andalas
  • Netti Suharti Universitas Andalas

DOI:

https://doi.org/10.59680/anestesi.v3i1.1594

Keywords:

Carcinoma of the larynx, clinicopathology, squamous cell carcinoma, glottis

Abstract

Laryngeal carcinoma is a cancer of the larynx that attacks the normal epithelium of the larynx. This carcinoma is the second most common type of head and neck epithelial malignancy in the world and the second most common in the respiratory tract after lung cancer. Carcinoma of the larynx has non-specific clinical manifestations, causing delayed early detection, thus affecting the management and prognosis of patients. This study aimed to determined the frequency distribution of laryngeal carcinoma patients based on gender, age, clinical manifestations, location, histopathological type, degree of differentiation. This research is a categorical descriptive study. The study sample was patients diagnosed by an ENT doctor as a primary malignancy of laryngeal carcinoma with confirmation from histopathological examination.The results of this study showed that the majority of laryngeal carcinoma patients were male (94%), the most age group was 59-65 years old (30.61%), the most common clinical manifestation was hoarseness (42.8%), The most common tumor location was in the glottis (92%), the most common histopathological features were squamous cell carcinoma (98%), and the highest degree of differentiation was moderate differentiation (36.73%). The majority of laryngeal carcinoma patients are men with an age range of 59-65 years. The most clinical manifestations were hoarseness, the most common tumor location was in the glottis, the most histopathological features were squamous cell carcinoma, and the highest degree of differentiation was moderate differentiation.

References

Amin, M. B., Edge, S. B., & Greene, F. L. (2018). AJCC cancer staging manual (8th ed.). North Kansas City Hospital.

Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394–424.

Cance, W. G., Makaroff, L., McCullough, M. L., Saslow, D., & Smith, R. (2021). What is throat cancer? What is hypopharyngeal cancer. American Cancer Society, 1(1), 1–8.

Ciolofan, M. S., Vl?escu, A. N., Mogoant?, C.-A., Ioni??, E., Ioni??, I., & C?pit?nescu, A.-N., et al. (2017). Clinical, histological and immunohistochemical evaluation of larynx cancer. Current Health Sciences Journal, 43(4), 367–375.

Ganapati, N. P. D. (2010). Profil epidemiologi penyakit kanker di Rumah Sakit Nasional Cipto Mangunkusomo tahun 2008-2010. (Skripsi). Jakarta: Fakultas Kedokteran Universitas Indonesia, p. 4.

Globocan. (2020). WHO South-East Asia region (SEARO). International Agency for Research on Cancer, 445, 1–2.

Koroulakis, A., & Agarwal, M. (2021). Laryngeal cancer. StatPearls Publishing, 1(1), 111.

Markman, M. (2021). Throat cancer symptoms. Cancer Treatment Centers of America, 1(1), 1–5.

Nocini, R., Molteni, G., Mattiuzzi, C., & Lippi, G. (2020). Updates on larynx cancer epidemiology. Chinese Journal of Cancer Research, 32, 18–25.

Noone, A. M., Howlader, N., Krapcho, M., Miller, D., Brest, A., & Yu, M., et al. (2019). Laryngeal cancer – cancer stat facts. NIH, 1(1).

Putri, I. P. (2019). Gambaran pasien karsinoma laring di bagian THT-KL RSUP Dr. Mdjamil Padang periode 1 Januari 2015–31 Desember 2017. (Skripsi). Padang: Fakultas Kedokteran Universitas Andalas, p. 45.

Shaghayegh, K., Mahdi, A., & Ali, K. (2010). Larynx preserving treatments in the early and advanced laryngeal cancers: A retrospective analysis. Journal of Cancer Science and Therapy, 2(1), 8–10.

Singh, R. K. A. J. (2016). Gambaran penderita karsinoma laring di Departemen THT-KL RSUP Haji Adam Malik Medan. (Skripsi). Medan: Fakultas Kedokteran Universitas Sumatera Utara, p. 337.

Soepardi, E. A., Iskandar, N., Bashiruddin, J., & Restuti, R. D. (2007). Telinga hidung tenggorok kepala & leher (Edisi Keenam). Jakarta: Fakultas Kedokteran Universitas Indonesia, 194–198.

World Health Organization (WHO). (2020). Globocan. International Agency for Research on Cancer, 1(1), 1–2.

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Published

2024-12-28

How to Cite

Fikri Akbar, Ade Asyari, & Netti Suharti. (2024). Gambaran Klinikopatologi Karsinoma Laring di Laboatorium Patologi Anatomi RSUP. Dr. M. Djamil Padang Tahun 2018 -2021. Jurnal Anestesi, 3(1), 68–81. https://doi.org/10.59680/anestesi.v3i1.1594