Diagnosis Dan Rencana Tatalaksana Chromoblastomycosis
DOI:
https://doi.org/10.59680/ventilator.v1i3.453Keywords:
Fungal Infection, ChromoblastomycosisAbstract
Chromoblastomycosis is a slowly progressive granulomatous skin infection caused by several species of black fungus such as Phialophora verrucosa, Fonsecaea pedrosoi, Rhinocladiella aquaspersa and Cladosporium carrionii. A case was found of a 51-year-old patient with a main complaint of a reddish, uneven lump, occasionally itchy, but not accompanied by pain in the right arm. On anatomic pathological examination, microscopic results were obtained in the form of epidermal skin tissue preparations that appeared hyperkeratosis, acanthosis, pseudoepitheliomatous hyperplasia. Intra-epidermal abscesses were seen with an accumulation of neutrophil inflammatory cells, lymphocytes, histiocytes and groups of epitheloid cells that formed granulomas. There was no sign of malignancy. The conclusion from the results of anatomical pathology readings is that there is a fungal infection (chromoblastomycosis). Treatment is given by oral itraconazole.
References
Brook GF. Butel JS. Morse SA. Jawetz, Melnick, & Adelberg’s Mikrobiologi Kedokteran. Penterjemah & editor?: Bagian Mikrobiologi FK Airlangga. Edisi 22. Jakarta: Salemba Medika; 2001. 280–281 p.
Hay RJ. Deep Fungal Infections. In: Goldsmith LA, Katz SI, Gilchrest, Paller AS, Leffell DJ, Wolff K, editors Fitzpatrick’s Dermatology in General Medicine. 8th ed. New York: McGraw Hill Publishing; 2012. p. McGraw Hill.
Baddley JW. Dismukes WE. Chromoblastomycosis. In: Kauffman CA, Pappas PG, Sobel JD, Dismukes WE, editors Essential of Clinical Mycology. 2nd ed. New York: Springer Science-Business Media; 2011. p. 427–31.
Verma S. Thakur BK. Raphael V. Thappa DM. Epidemiology of Subcutaneous Mycoses in Northeast India: A Retrospective Study. Indian J Dermatology. 2018;63(6):496–501.
Brito AC. Bittencourt MJS. Chromoblastomycosis: An Etiological, Epidemiology, Clinical, Diagnostic, and Treatment Update. An Bras Dermatol. 2018;93(4):495–506.
Angadi KM. Misra RN. Gandham NR. Moumita S. Vyawahare. Singhania SS. et al. Chromoblastomycosis: A Rare Case of Infection by Fonsecaea Compacta From Western Maharashtra, India. Int J Microbiol Res. 2012;4(9):330–1.
Minotto R. Bernardi CDV. Mallmann LF. Edelweiss MIA. Scroferneker ML. Chromoblastomycosis: A Review of 100 Cases in the State of Rio Grande do Sul, Brazil. J Am Acad Dermatol. 2001;44:585–92.
Yahya S. Widaty S. Miranda E. Bramono K. Islami A w. Subcutaneous Mycosis at the Department of Dermatology and Venereology dr. Cipto Mangunkusumo National Hospital, Jakarta, 1989-2013. J Gen Pro DVI. 2016;1(2):36–43.
Queiroz-Telles F. McGinnis MR. SalkinI. Graybill JR. Subcutaneous Mycoses. Infect Dis Clin North Am. 2003;17(1):59–85.
Khan I. Khan RA. Khan SM. Clinicopathological Study of Cutaneous Chromoblastomycosis in Pakistan. J Pakistan Assoc Dermatologists. 2012;22:122–5.
Chandran V. Sadanandan SM. Sobhanakumari. Chromoblastomycosis in Kerala, India. Indian J Dermatology, Venerol Leprol. 2012;78:728–33.
Kang Sewon. Amagai Masayuki. Bruckner AL. Alexander H. Margolis DJ. McMichael AJ. Orringer JS., editor. Fitzpatrick’s Dematology. Volume 1. 9th Editio. New York: McGraw Hill Education; 2019. 2971–2972 p.
