Hubungan Kebutuhan Continuous Renal Replacement Therapy (CRRT) dengan Mortalitas pada Pasien Acute Kidney Injury (AKI) di Intensive Care Unit (ICU)
DOI:
https://doi.org/10.59680/anestesi.v4i3.2422Keywords:
Acute Kidney Injury, Continuous Renal Replacement Therapy, Hemodynamic instability, ICU, MortalityAbstract
Acute Kidney Injury (AKI) is one of the most serious complications in critically ill patients admitted to the Intensive Care Unit (ICU). Continuous Renal Replacement Therapy (CRRT) is the preferred renal replacement therapy modality for AKI patients with hemodynamic instability; however, the mortality rate remains very high. This study aims to analyze the relationship between the need for CRRT and mortality in AKI patients in the ICU. A retrospective cohort study was conducted on 30 AKI patients treated in the ICU at Mohammad Hoesin Hospital in Palembang from January 1, 2023 to December 31, 2025. Inclusion criteria included age >= 18 years and admission to the ICU with a diagnosis of AKI requiring CRRT; patients with incomplete medical records, those undergoing intermittent hemodialysis, or with a history of chronic kidney disease were excluded. Data were analyzed using Fisher's exact test. The mortality rate was 86.7 percent (26/30). The most common indication for CRRT was diuretic resistant fluid overload (50 percent). Neither the type nor the number of CRRT indications was significantly associated with mortality (p > 0.05 for all comparisons). The need for CRRT was not significantly associated with mortality in AKI patients in the ICU. The clinical conditions requiring CRRT inherently reflect a uniformly high risk of death, regardless of the specific type or number of indications.
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