Pengaruh Jenis General Anestesi pada Acute and Chronic Postoperative Pain pada Pasien Kanker Systematic Literature Review
DOI:
https://doi.org/10.59680/anestesi.v4i3.2408Keywords:
Cancer, CPSP, General Anesthesia, Inhalation Anesthesia, Postoperative PainAbstract
Postoperative pain in cancer patients is a common complication that may significantly affect long-term quality of life. The type of general anesthesia is suggested to play a role in modulating both acute pain and chronic postsurgical pain (CPSP). This study aimed to evaluate the effect of different types of general anesthesia on postoperative pain through a systematic literature review based on PRISMA guidelines. Literature searches were conducted in PubMed, ScienceDirect, and Google Scholar, yielding 8,616 articles. After screening and quality assessment using the Joanna Briggs Institute (JBI) tool, nine studies were included in the analysis. The results showed that total intravenous anesthesia (TIVA) based on propofol tended to reduce postoperative analgesic requirements compared to inhalational anesthesia. In addition, several studies reported that TIVA was associated with a reduced risk of CPSP, although the findings across studies were not fully consistent. Other factors, such as surgical technique and patient characteristics, also contributed to postoperative pain outcomes. In conclusion, propofol-based TIVA may offer advantages in postoperative pain management. However, since postoperative pain is multifactorial, an individualized approach and multimodal pain management strategies are required to optimize outcomes in cancer patients.
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