Penatalaksanaan Penyinaran Radioterapi Eksterna Pada Kanker Vagina Menggunakan Teknik Intensity Modulated Radiation Therapy (IMRT) Di Cancer Center Radioterapi Santosa Hospital Bandung Kopo
DOI:
https://doi.org/10.59680/ventilator.v1i4.783Keywords:
Vaginal Ca External Radiation, Radiotherapy, TumorsAbstract
Management Of External Radiotherapy Irradiation In Vaginal Cancer Using Intensity Modulated Radiation Therapy (IMRT) Technique At The Cancer Center Radiotherapy Santosa Hospital Bandung Kopo. Vaginal carcinoma constitutes approximately 2% of all malignant neoplasms that occur in the female genital tract. Vaginal carcinoma can arise from various types of cells within the vaginal wall and is often associated with risk factors such as exposure to certain carcinogens (8). Cancer is one of the main causes of death throughout the world. Based on GLOBOCAN data, the International Agency for Research on Cancer (IARC) in 2018, deaths caused by cancer reached around 9.5 million people, with 60% of cancer deaths in Asia. (7) Radiotherapy is a cancer treatment approach that uses light. ionizer to damage tumor cells while maintaining the integrity of surrounding healthy tissue. The main focus is to eliminate as many cancer cells as possible while reducing the negative impact on normal tissue around the tumor area. (20) There are several treatments for patients suffering from vaginal cancer, namely surgery, radiation, brachytherapy, and external radiation based on the size and stage of the tumor suffered by the patient. (3) Based on the book "Target Volume Dileniation And Filed Setup" (a practical guide for conformal and Intensity-Modulated Radioation Therapy), Arno.J, (2013: 201), all vaginal cancer patients who undergo radiation using the IMRT technique must simulated in a supine position and the patient's legs straight with a thermoplastic immobilization mask and adjusted immobilization of the upper and lower body (16).
References
Alfiah F. Analisis Tingkat Konsistensi Lapangan Penyinaran Radiasi Eksterna Pada Pasien Metastase Tumor Tulang Belakang Dengan Menggunakan Alat Immobilisasi Masker Thermoplast. Poltekkes Jakarta 2; 2012
American Cancer Society. Cancer Facts and figure 2017.
Anak Agung Sagung Ari Lestari, Nana Supriana Radioterapi & Onkologi Indonesia Vol.8 (1) Jan. 2017:13-26
Donaladson S liam. Radiotherapy risk profile. Vol. 49, World Health Organization. Geneva: WHO; 2020. 282-285 p.
Fitriatuzzakiyyah N, Sinuraya RK, Puspitasari IM. “Cancer Therapy with Radiation: The Basic Concept of Radiotherapy and Its Development in Indonesia”. Indones J Clin Pharm. 2017;6(4):311–20
Gadducci A, Fabrini MG, Lanfredini N.Squamous cell carcinoma of the vagina: natural history, treatment modalities, and prognostic factors. Critical reviews in Oncology/Hematology. 2015;93: 211-224.
GLOBOCAN. 2018. Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. (Online). (https://gco.iarc.fr/today, diakses 20 Agustus 2020).
Hacker NF. Vaginal Cancer. In: Berek JS, Hacker NF, editors. Berek and Hacker’s Gynecologic Oncology. 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2015. p. 608–24
Khan FM, Gibbons JP. “THE PHYSICS OF RADIATION THERAPY. 5thed”. Philadelphia: Wolters Kluwer; 2014. 565p
K Kartutik.”Comparison of RadioTheapy Dosimetry for 3D-CRT, IMRT, and SBRT based on Electron Density Calibration”. Journal of Physics: Conference Series. 2016 (012017)
Lee LJ, Jhingran A, Kidd E, Gaffney DK, Higinia RC, Elshaikh MA, et al. Management of Vaginal cancer. American College of Radiology ACR Appropriatness Criteria. 2013.
Lemien A, Forss M, Lehtovirta P. Therapeutic and prognostic considerations in primary carcinoma of the vagina. Acta Obstet Gynecol Scand 1995; 74: 379-383.
Moore KL, Dalley AF, Agur AMR. 2014. Moore clinically oriented anatomy. Edisi ke-7. Baltimore: Lippincott Williams & Wilkins.
Mutic S, Purdy JA, Michalski JM, Perez CA. “The Simulation Process in the Determination and Definition of the Treatment Volume and Treatment Planning”. Tech Basis Radiat Ther. 2016;107–33.
Nuryaman Banida Ismil, Darmini, Kartikasari Yetti, Wibisono Danu. “Volumetric Modulated Arc Therapy Technique In Cases Of Tongue Cancer In Radiation Oncology Instlation Mrccc Siloam”. Journal of Applied Health Management and Technology Vol 4, No 3 (2022) Page 75-79
N.Y. Lee, J.J. Lu (eds.), Target Volume Delineation and Field Serup,De DOI 10.1007/978-3-642-28860-9_22, 0 Springer- Verlag Berlin Heidelteryg 2013
Pipman Y. We all know about Linear Accelerators. 2017;
Rosenblatt E, Head S, Biology AR. Defining Target Volumes and Organs at Risk : a common language Objective : To introduce target volumes and organ at. 2019;
Podgorsak EB. “Radiation Oncology Physics : A Handbook for Teachersand Students”. 2015.
Togibasa, O. (2015). Perhitungan Laju Dosis Serap Menggunakan Metode Monte Carlo. SAINS: Jurnal MIPA dan Pengajarannya.
Wali Tomas, Anita Febria. “Verifikasi Distribusi Dosis TPS Dan Pesawat Linac Menggunakan Phantom Octavius 4D Dengan Teknik IMRT Protokol Kanker Lidah”. Jurnal Ilmiah GIGA Volume 20 (2) November 2017 Halaman 38-43.
