Epidural Blood Patch for Severe Post-Dural Puncture Headache in a Hypertensive Patient Following Spinal Anesthesia: A Case Report

Authors

  • Maulfi Natsir Asy’ari RSUD dr. Soediran Mangun Sumarso Wonogiri
  • Yosie Arief Sanjaya Universitas Islam Indonesia
  • Nafi Ilhamsyah Universitas Islam Indonesia
  • Alfi Sachdeva Aziz Waktar Universitas Islam Indonesia
  • Arsya Malika Arief Universitas Muhammadiyah Yogyakarta

DOI:

https://doi.org/10.59680/ventilator.v4i1.2495

Keywords:

Cerebrospinal Fluid, Epidural Blood Patch, Hypertension, Post-Dural Puncture Headache, Spinal Snesthesia

Abstract

Post-dural puncture headache (PDPH) is a frequent complication following neuraxial anesthesia, resulting from cerebrospinal fluid (CSF) leakage and intracranial hypotension. Although typically self-limiting, severe PDPH can significantly impair patient function and delay recovery. Epidural blood patch (EBP) is considered the gold standard treatment for refractory cases; however, optimal volume and clinical considerations in patients with comorbidities such as hypertension remain underreported. We report a 45-year-old female with a history of hypertension who developed severe PDPH following spinal anesthesia for lymphadenectomy. The procedure required multiple attempts using a 25G Quincke needle. Within hours postoperatively, the patient experienced a classic orthostatic headache accompanied by photophobia, nausea, and inability to tolerate an upright position. Conservative management failed to provide improvement after 48 hours. An epidural blood patch using 10 mL of autologous blood was subsequently performed, resulting in rapid and significant symptom relief within one hour, followed by progressive clinical recovery over the next two days. This case highlights the importance of early recognition and timely intervention in PDPH, particularly in patients with overlapping symptoms such as hypertension. Notably, a lower-volume EBP (10 mL) demonstrated effective clinical outcomes, suggesting that individualized approaches may be sufficient in selected patients. Epidural blood patch remains a safe and effective definitive treatment for refractory PDPH.

References

Apfel, C. C., Saxena, A., Cakmakkaya, O. S., Celik, M., Shilling, A., & Gamble, J. G. (2010). Prevention of post-dural puncture headache: A systematic review. Anesthesia & Analgesia, 110(2).

Bezov, D., Lipton, R. B., & Ashina, S. (2010). Post-dural puncture headache: Part I diagnosis, epidemiology, etiology, and pathophysiology. Headache: The Journal of Head and Face Pain, 50(7). https://doi.org/10.1111/j.1526-4610.2010.01699.x

Boonmak, P., & Boonmak, S. (2010). Epidural blood patching for preventing and treating post-dural puncture headache. Cochrane Database of Systematic Reviews, (1), CD001791. https://doi.org/10.1002/14651858.CD001791.pub2

Butterworth, J. F., Mackey, D. C., & Wasnick, J. D. (2013). Morgan & Mikhail's clinical anesthesiology (5th ed.). McGraw-Hill Education.

Fitzpatrick, M., & Bourke, B. (2019). The role of caffeine in managing post-dural puncture headache: A narrative review. Irish Journal of Medical Science, 188(4).

Frank, R. L. (2007). Lumbar puncture and post-dural puncture headaches: Implications for the emergency physician. Journal of Emergency Medicine, 35(2). https://doi.org/10.1016/j.jemermed.2007.03.024

Ghaleb, A. (2010). Postdural puncture headache. Anesthesia Research and Practice, 2010, Article 102967. https://doi.org/10.1155/2010/102967

Gupta, A., Heymann, C. V., Magnuson, A., et al. (2020). Management practices for postdural puncture headache in obstetrics: A prospective, international, cohort study. British Journal of Anaesthesia. https://doi.org/10.1016/j.bja.2020.07.061

Hadzic, A. (2007). Textbook of regional anesthesia and acute pain management. McGraw-Hill.

Hadzic, A. (2017). Hadzic's textbook of regional anesthesia and acute pain management (2nd ed.). McGraw-Hill Education.

Hasan, A. S., Ekram, A. S., Rahman, S. W., et al. (2002). Meningeal irritation: A review. TAJ: Journal of Teachers Association, 15(2). https://doi.org/10.3329/taj.v15i2.3922

Headache Classification Committee of the International Headache Society (IHS). (2018). The international classification of headache disorders (3rd ed.). Cephalalgia, 38(1). https://doi.org/10.1177/0333102417738202

Jabbari, A., Alijanpour, E., Mir, M., et al. (2013). Post spinal puncture headache, an old problem and new concepts: Review of articles about predisposing factors. Caspian Journal of Internal Medicine, 4(1).

Katz, D., Beilin, Y., & Cohen, J. (2010). Post-dural puncture headache: Risk factors, pathophysiology, prevention and treatment. Headache, 50(9).

Kwak, K. H. (2017). Postdural puncture headache. Korean Journal of Anesthesiology, 70(2). https://doi.org/10.4097/kjae.2017.70.2.136

Miller, R. D., Eriksson, L. I., Fleisher, L. A., Wiener-Kronish, J. P., & Cohen, N. H. (2020). Miller's anesthesia (9th ed.). Elsevier.

Morgan, G. E., Mikhail, M. S., & Murray, M. J. (2018). Clinical anesthesiology (6th ed.). McGraw-Hill Education.

Omole, O. B., & Ogunbanjo, G. A. (2015). Postdural puncture headache: Evidence-based review for primary care. South African Family Practice, 57(4). https://doi.org/10.1080/20786190.2015.1014154

Roldan, C. J., Chung, M., McCarty, C., et al. (2020). High-flow oxygen and pro-serotonin agents for non-interventional treatment of post-dural-puncture headache. American Journal of Emergency Medicine. https://doi.org/10.1016/j.ajem.2020.07.076

Safra-Tisseront, V., Thormann, F., Malassiné, P., Henry, M., Riou, B., & Coriat, P. (2001). Effectiveness of epidural blood patch in the management of post-dural puncture headache. Anesthesiology, 95(2). https://doi.org/10.1097/00000542-200108000-00012

Shaikh, S. I., & Ramesh, N. K. (2015). Perioperative management of post dural puncture headache. International Journal of Basic and Applied Research, 6(2). https://doi.org/10.7439/ijbar.v6i2.1557

Turnbull, D. K., & Shepherd, D. B. (2003). Post-dural puncture headache: Pathogenesis, prevention, and treatment. British Journal of Anaesthesia, 91(5). https://doi.org/10.1093/bja/aeg231

Turnbull, D. K., & Shepherd, D. B. (2003). Post-dural puncture headache: Pathogenesis, prevention and treatment. British Journal of Anaesthesia, 91(5). https://doi.org/10.1093/bja/aeg231

Downloads

Published

2026-03-31

How to Cite

Maulfi Natsir Asy’ari, Yosie Arief Sanjaya, Nafi Ilhamsyah, Alfi Sachdeva Aziz Waktar, & Arsya Malika Arief. (2026). Epidural Blood Patch for Severe Post-Dural Puncture Headache in a Hypertensive Patient Following Spinal Anesthesia: A Case Report. Jurnal Ventilator, 4(1), 405–414. https://doi.org/10.59680/ventilator.v4i1.2495

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.